Showing posts with label organophosphorus. Show all posts
Showing posts with label organophosphorus. Show all posts

Sunday, June 2, 2013

OP Poisoning

A common term in most of the emergencies of hospitals in South East Asian countries, OP poisoning stands for organophosphate poisoning. 


We had the worst OP poisoning case ever in the annals of NJH couple of days back. 

SHD, a 26 year old, mother of 3, had gulped down an entire 120 ml bottle of Malathion after a tiff with her hubby. When she arrived, we had to literally pour Atropine down her veins to ensure that she remained asymptomatic. It was only after we had given about 3500 mgs of Atropine over 24 hours that she stabilised. 

Over the next day, we had weaned her out of the ventilator. However, we were very sure that 'Intermediate Syndrome' was just around the corner. I prayed that it would happen when we are around during daytime. 

But, that was not to be. I was just getting ready to hit the bed when she went into respiratory arrest. Dr. Shishir was operating on a severe pre-eclampsia patient with fetal distress when it happened. 

By God's grace, we've been successful in getting her well supported. Again, the staff in ACU did a magnificent job. The presence of mind and diligence was all the more evident as there were 3 eclampsia patients in the ACU

The next 24 hours are going to be crucial. 

We request prayers that she will be completely healed . . . and of course, specialist advice is definitely welcome. 

Wednesday, July 18, 2012

Pesticide poisoning . . . A point

The last 2 days, I had a very unique problem with 2 patients. 

The first one was a young lady who had come in unconscious since the last 24 hours and was being managed elsewhere. There was no definitive diagnosis. From the history and examination findings, there were only 2 possibilities. . . It was either a pontine bleed or an organophosphorus poisoning. 

The relatives vehemently denied the possibility of a poisoning. 

As she was not breathing well, we had her intubated in no time. While intubating, we noticed that there was quite a lot of secretions in the airway. 

Nothing much happened initially. We had given the option of a referral which the relatives were not very much interested in.

We weighed the options and started off her on Atropine to which she amazingly responded. By today morning, she was sitting up and it was quite heartening to see the sight . . .

 Later today, a little boy came in gasping, frothing from the mouth and with pin point pupils. He had eaten some poison which was kept on the window ledge. Here, the parents were sure on what was eaten. . . For me, it was pure organophosphorus. He responded to the same management which we gave for the former lady except for the ventilation. 

This is the fourth or fifth time that patients have come in after ingesting poisons accidently (at least from the history). I remember one of them which I thought was homicidal. 

I remember being taught that free availability of poisons is one of the major causes of accidental and self inflicted poisoning in most of the Asian countries where it is common.

When the parents of the boy showed me the sachet of the poison, it was not difficult to realise the reason on why accidental poisoning is something we need to consider seriously when patients come unconscious to our emergency rooms.

Below is the snap of the sachet.


A common practice in India to decrease the cost of purchase of many an item, sachets such as these are quite a dangerous thing. Taken out from their original packing, these poisons are repacked into unlabelled packets. I showed it to couple of our staff who use pesticides for farming purposes. I asked them about the poison. They did not have any idea other than that it was very good to kill houseflies. 

The shiny substance inside the sachet is quite attractive for children. Many a time I've seen liquid pesticides repacked inside empty cough syrup bottles. Last year, we had one young man who claimed to have unknowingly drank Malathion which was stored inside a cough syrup bottle. He was lucky to have made it alive.

In the prevention of pesticide poisoning, one of the concepts being promoted is to ensure that purchase of pesticides be monitored and there is community based storage of pesticides. Of course it is important. However, more important is the need for public awareness not to store it outside their labelled bottles or sachets and not to sell or store pesticides in loose unlabelled packets.

Well, regarding the first patient, the lady - I got a history from her that she was having headache and she had taken some medicine which was given to her long ago. . . She does not remember anything after she took that medicine. My hunch is that she has taken some organophosphorus poison which was kept in an unlabelled bottle. In fact, we had got the history of a headache from the husband . . .from which we had kept the probability of a intracranial bleed -  a pontine hemorrhage because of the pin point pupil . . .

So, any unconscious patient from now on . . . we would be looking at possibilities of poisoning seriously.